Best Compounds for Erectile Function

Compounds studied for erectile function, PDE5 inhibition, blood flow, and sexual performance.

9 compounds ranked by research effectiveness

01

Tadalafil

FDA Approved

PDE5 Inhibitor | Erectile Function & Blood Flow

Erectile Dysfunction most effective
Sexual Confidence & Spontaneity most effective
Half-life: ~17.5 hours
02

Sildenafil

FDA Approved

PDE5 Inhibitor | Erectile Function & Pulmonary Hypertension

Erectile Dysfunction most effective
Sexual Performance most effective
Half-life: ~3-5 hours
03

PT-141

FDA Approved

Melanocortin Receptor Agonist | Sexual Dysfunction Treatment

Hypoactive Sexual Desire Disorder (HSDD) most effective
Erectile Dysfunction effective
Female Sexual Arousal Disorder effective
Half-life: ~2.7 hours
04

Kisspeptin

Emerging

KISS1 Gene Product | Reproductive Neuropeptide

Hypoactive Sexual Desire Disorder (Men) effective
Hypoactive Sexual Desire Disorder (Women) effective
Half-life: ~4 minutes (KP-10), ~28-32 minutes (KP-54)
05

Testosterone

FDA Approved

Anabolic-Androgenic Steroid | Primary Male Sex Hormone

Erectile Dysfunction effective
Libido Restoration most effective
Sexual Satisfaction effective
Half-life: ~8 days (cypionate)
06

Dapoxetine

FDA Approved

SSRI | Premature Ejaculation Treatment

Premature Ejaculation most effective
Sexual Satisfaction effective
Half-life: ~1.5 hours
07

Proviron

Well Studied

DHT Derivative | Mood, Libido & Muscle Hardening

Libido Enhancement most effective
Erectile Quality effective
Male Infertility (Low-Dose) moderate
Half-life: ~12 hours
08

Melanotan II

Well Studied

Synthetic Melanocortin Peptide | Tanning & Sexual Function

Enhanced Libido effective
Erectile Function effective
Female Sexual Arousal effective
Half-life: ~2 hours
09

MENT

Emerging

19-Nor Anabolic Steroid | Experimental TRT Alternative

Libido and Sexual Function Maintenance effective
Half-life: ~40 minutes (acetate ester)

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