Best Compounds for Sexual Health & Fertility

Peptides studied for sexual function, libido, fertility, and reproductive health.

14 compounds ranked by research effectiveness

01

PT-141

FDA Approved

Melanocortin Receptor Agonist | Sexual Dysfunction Treatment

Hypoactive Sexual Desire Disorder (HSDD) most effective
Erectile Dysfunction effective
Female Sexual Arousal Disorder effective
Half-life: ~2.7 hours
02

Kisspeptin

Emerging

KISS1 Gene Product | Reproductive Neuropeptide

Hypogonadotropic Hypogonadism most effective
IVF Ovulation Trigger most effective
Hypothalamic Amenorrhea effective
Hypoactive Sexual Desire Disorder (Men) effective
Hypoactive Sexual Desire Disorder (Women) effective
Half-life: ~4 minutes (KP-10), ~28-32 minutes (KP-54)
03

Gonadorelin

Extensively Studied

Gonadotropin-Releasing Hormone | GnRH Agonist

Hypogonadotropic Hypogonadism most effective
Ovulation Induction most effective
Male Fertility effective
Delayed Puberty effective
Half-life: 2-4 minutes
04

HCG

FDA Approved

Human Chorionic Gonadotropin | LH Receptor Agonist

TRT Adjunct most effective
Hypogonadotropic Hypogonadism most effective
Post-Cycle Therapy effective
Ovulation Induction most effective
Half-life: 24-36 hours
05

HMG

Extensively Studied

Human Menopausal Gonadotropin | FSH/LH Fertility Hormone

Ovulation Induction most effective
IVF Stimulation most effective
PCOS Ovulation effective
Spermatogenesis effective
Hypogonadotropic Hypogonadism effective
LH Replacement moderate
Half-life: ~32 hours (FSH component: 39-54 hours)
06

Sildenafil

FDA Approved

PDE5 Inhibitor | Erectile Function & Pulmonary Hypertension

Erectile Dysfunction most effective
Sexual Performance most effective
Half-life: ~3-5 hours
07

Tadalafil

FDA Approved

PDE5 Inhibitor | Erectile Function & Blood Flow

Erectile Dysfunction most effective
Sexual Confidence & Spontaneity most effective
Half-life: ~17.5 hours
08

Testosterone

FDA Approved

Anabolic-Androgenic Steroid | Primary Male Sex Hormone

Erectile Dysfunction effective
Libido Restoration most effective
Sexual Satisfaction effective
Half-life: ~8 days (cypionate)
09

Dapoxetine

FDA Approved

SSRI | Premature Ejaculation Treatment

Premature Ejaculation most effective
Sexual Satisfaction effective
Half-life: ~1.5 hours
10

Proviron

Well Studied

DHT Derivative | Mood, Libido & Muscle Hardening

Libido Enhancement most effective
Erectile Quality effective
Male Infertility (Low-Dose) moderate
Half-life: ~12 hours
11

Testagen

Moderate Research

KEDG Tetrapeptide | Testicular Bioregulator

Low Testosterone effective
HPG Axis Restoration effective
Age-Related Testosterone Decline moderate
Male Fertility Support moderate
Testicular Function moderate
Sexual Function moderate
Half-life: Not established
12

Melanotan II

Well Studied

Synthetic Melanocortin Peptide | Tanning & Sexual Function

Enhanced Libido effective
Erectile Function effective
Female Sexual Arousal effective
Half-life: ~2 hours
13

Enclomiphene

Well Studied

Selective Estrogen Receptor Modulator | Testosterone & Fertility Support

Spermatogenesis Support effective
Fertility Preservation on TRT Bridge effective
Half-life: ~10 hours
14

MENT

Emerging

19-Nor Anabolic Steroid | Experimental TRT Alternative

Libido and Sexual Function Maintenance effective
Half-life: ~40 minutes (acetate ester)

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